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SPRAVATO®: Depression Treatment for Antidepressant Resistance

SPRAVATO®: Depression Treatment for Antidepressant Resistance

What is SPRAVATO®?

It is incredibly demoralizing to have a mood disorder that resists treatment again and again. It can feel like your last hope has failed you. But one of the great things about mental health care is that they are constantly working on new ways of treating people–and we’d like to introduce you to a wonderful alternative treatment.

SPRAVATO®, also known as esketamine, is a nasal spray that is self-administered by the patient while being monitored by a specially trained medical assistant at regular intervals. It is taken alongside other antidepressants and therapy, targeting different neural receptors in the brain. Is has been shown to aid in decreasing depression and restoring stability to patients’ moods.

How does SPRAVATO® work?

“Esketamine is the first new medication for depression in many years with a totally different mechanism of action,” says Dr. Vaishnavi, MindPath’s neuropsychiatric expert. “It can act quickly, potentially in days rather than weeks or months, and it may work for patients when previous medications have not.”

Various trials have shown SPRAVATO® to be quite effective. After 16 weeks of therapy, those patients who stayed on SPRAVATO® did better than those who stopped therapy and showed a greater reduction of depression symptoms than those who received only an oral antidepressant.

SPRAVATO® is only available at certified SPRAVATO® treatment centers under the supervision of a healthcare provider.

For more information, including potential side effects and other risks and benefits, please visit the SPRAVATO® website >

How can I get started with SPRAVATO®?

To see if SPRAVATO® is right for you, please complete the form below to request your free assessment. If you have questions or concerns, please contact us at 877-876-3783 and our intake team will be happy to help.

Many major commercial and Medicare plans now cover SPRAVATO® treatment for depression. MindPath Care Centers now accepts Medicare, BCBS, Cigna, Aetna, and Tricare for SPRAVATO® treatment. As with other medical treatments, contact your specific insurance provider to confirm whether SPRAVATO® is covered for you.

Request a Free Online Assessment

  • After clicking submit, you will be emailed a digital assessment form to complete.

SPRAVATO® Certified Clinicians

Director – Sandeep Vaishnavi, MD, PhD

  • MD in Psychiatry from the University of Alabama
  • Residency in Psychiatry at Duke University
  • Residency in Clinical Psychopharmacology at Duke University and GlaxoSmithKline
  • Fellowship in Behavioral Neurology and Neuropsychiatry at Johns Hopkins University School of Medicine
  • Double board-certified – Behavioral Neurology & Neuropsychiatry and General Psychiatry
  • E. Elise Herman

    Psychiatrist

    E. Elise Herman

    MD

    Psychiatrist

    Charlotte, NC

    E. Elise Herman

    MD

    I offer medication management

    • Adjustment Concerns
    • Alcohol Use
    • Anxiety / Stress
    • Bipolar I & II
    • Depression
    • LGBTQ+ Care
    • OCD
    • Post-Partum / Pregnancy Depression
    • PTSD/Trauma
    • badge-3 Telehealth
    • badge-4 TMS

    In-network with:

    • BCBS
    • Cigna
    • Tricare
    • Magellan
    • Medcost
    • Medicare
    • UBH
  • Jenny Smith

    Psychiatrist

    Jenny Smith

    MD

    Psychiatrist

    Raleigh, NC | Telehealth

    Jenny Smith

    MD

    I offer medication management and telehealth

    • ADD/ADHD
    • Adjustment Concerns
    • Alcohol Use
    • Anxiety / Stress
    • Bipolar I & II
    • Depression
    • Eating Disorder
    • OCD
    • Post-Partum / Pregnancy Depression
    • PTSD/Trauma
    • badge-3 Telehealth

    In-network with:

    • Aetna
    • BCBS
    • Tricare
    • Medicare
    • UBH
    • Humana
    • Worker’s Comp
    • Gateway
    • Alignment
  • Caleb Alan Whitenack

    Psychiatrist

    Caleb Alan Whitenack

    MD

    Psychiatrist

    Durham, NC | Telehealth

    Caleb Alan Whitenack

    MD

    I offer medication management and telehealth

    • Post-Partum / Pregnancy Depression
    • Transcranial Magnetic Stimulation (TMS)
    • badge-3 Telehealth
    • badge-4 TMS

    In-network with:

    • Aetna
    • BCBS
    • Cigna
    • Tricare
    • Magellan
    • Medcost
    • UBH
    • Alignment

What our Patients Say

I’ve struggled with depression for most of my life. I would spend 18 to 20 hours a day sleeping. I couldn’t physically do anything and had to drop out of college. I tried a long list of antidepressants but none of them worked for me. Spravato has made a big difference in my depression symptoms. I’m back in college full time now and growing as a person.

Results may vary according to individual.

SPRAVATO® Certified Locations

MindPath Care Centers
1130 Situs Court, Suite 109
Raleigh, NC 27606

Durham MindPath Care Centers location

MindPath Care Centers
4220 Apex Hwy, Ste 200
Durham, NC 27713

MindPath Care Centers
6060 Piedmont Row Dr S, Ste 500
Charlotte, NC 28287

Tropical Storm Isaias is headed towards the Carolinas

Tropical Storm Isaias is headed towards the Carolinas. Please note that we plan to be open for appointments; however, be aware that power outages may be widespread which may impact telehealth and other appointments. We may not know until the last minute in all of our locations on Tuesday. Please be patient. We will waive missed appointment charges on Tuesday, August 4th in light of complications from the weather. If you and your provider are unable to connect, we will reach out to reschedule your appointment as soon as possible.